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Abstract: in fl ammatory cholestatic liver the bile duct. PBC is frequently associated with varying degrees of liver fi brosis measured by fi broscan. as in fl ammation, cytokine signaling, and abnormalinteractionamongst cholangiocytesand mesenchymalcells contributetothe development of fi brosis. Firstlinetreatment is ursodiol (UDCA) therapy. This study aims to elucidate the consequences of liver fi brosis on the...
Abstract: Introduction: Non-alcoholicsteatohepatitis(NASH)isbecomingincreasinglyprevalentandaleadingcauseof cirrhosis.Unfortunately,besideslifestylechanges, therapeuticoptionsspeci fi callytargetingNASH are limited. Previous single center studies have suggested that glucagon-like peptide receptor (GLP1) agonists and sodium glucose co-transporter-2 (SGLT2)inhibitors may have a bene fi cial e ff ect. We sought t...
Abstract: Introduction: Post-hospital discharge (PHD) clinics aim to prevent readmissions and cut healthcare costs. This is important in patients with liver disease who require close monitoring of labs, symptoms and complications. We anticipate that by mitigating hospital necessitating treatments, PHD appointments will reduce readmission rates. Methods: A retrospective chart review was performed of 258 pati...
Abstract: [1023] Figure 1. Proportions of patients with an Inflammatory Bowel Disease Questionnaire total score $ 170 among patients at a) Week 8 of OCTAVE Induction 1&2[a] and b) Week 52 of OCTAVE Sustain[a] and in the c) tofacitinib 5 mg BID[b] and d) tofacitinib 10 mg BID[b] groups in OCTAVE Open, stratified by age. Values above brackets show the treatment difference from placebo (95% CI) [a] Non-respond...
Abstract: of ustekinumab and vedolizumab on intestinal resection rates in bio-na¨ ı ve CD patients. Methods: A commercial database (Explorys Inc, Cleveland, OH) was utilized, which included electronic health record data from 26 major integrated US healthcare systems. We identi fi ed bio-na¨ ı ve CD patients. The primary outcome was to examine the association between anti-tumor necrosis factor (anti-TNF) medi...
Abstract: Planning is a critical function of multi-agent autonomous systems, which includes path finding and task scheduling. Exhaustive search-based methods such as model checking and algorithmic game theory can solve simple instances of multi-agent planning. However, these methods suffer from state-space explosion when the number of agents is large. Learning-based methods can alleviate this problem, but la...
Abstract: As software engineering (SE) practitioners, we can help society by using our communities of experts to address a software need of a socially conscious organization. Doing so can benefit society in the locale of a SE conference and provide access to international experts for local organizations. Furthermore, established SE researchers as well as practitioners and students have the opportunity for a...
Abstract: —In the multi-commit development model, programmers complete tasks ( e . g ., implementing a feature) by organizing their work in several commits and packaging them into a commit-set. Analyzing data from developers using this model can be useful to tackle challenging developers’ needs, such as knowing which features introduce a bug as well as assessing the risk of integrating certain features in a...
Abstract: In construction machinery, connectivity delivers higher advantages in terms of higher productivity, lower costs, and most importantly safer work environment. As the machinery grows more dependent on internet-connected technologies, data security and product cybersecurity become more critical than ever. These machines have more cyber risks compared to other automotive segments since there are more ...
Abstract: The paper presents an approach to solve the software and hardware related failures in edge-cloud environments, more precisely, in cloud manufacturing environments. The proposed approach, called TOLERANCER, is composed of distributed components that continuously interact in a peer to peer fashion. Such interaction aims to detect stress situations or node failures, and accordingly, TOLERANCER makes ...
Abstract: In this paper, we present our ongoing work on proposing solutions to integrate legacy end-stations into Time-Sensitive Network (TSN) communication systems where the legacy end-stations are synchronized via their legacy clock synchronization protocol. To this end, we experimentally identify the effects of lacking synchronization or partial synchronization in TSN networks. In the experiments we show...
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